We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.
Synonyms: TPGS-750-M
Linear Structural Formula: (C2H4O)nC34H56O5
Density: 0.981 g/mL at 25 C
Refractive Index: n20/D 1.340
Application: Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.Included among the possible reactions are:
•Olefin metathesis
•Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
•C-H activation reactionsSecond generation amphiphile for cross-coupling reactions in water
Other Notes: Watch Professor Lipshutz talk about TPGS-750-M in this webinar:From milligrams to kilograms: synthetic chemistry following nature's lead