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Synonyms: Dienogest; (17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one
Molecular Formula: C20H25NO2
Molecular Weight: 311.42
Linear Structural Formula: C20H25NO2
MDL Number: MFCD00868356
Biochem Physiol Actions: Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.
Other Notes: Sales restrictions may apply.