DCDAPH (1,1-dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) is a far-red fluorescent probe that has proved to have affinity to Aβ plaques. It has been used for fluorescent staining of brain sections, as well as in vivo detection of Aβ1-42 aggregates by small animal near-IR imaging. DCDAPH has high affinity (Ki= 37 nM, Kd=27 nM) to Aβ1-42 aggregates.
- Dark purple solid
- &lamba;Ex/&lamba;Em = 597/665 nm (PBS)
- Store at -20°C and protect from light, especially in solution
- C16H15N3
- MW: 249.31