Synonyms: (6S)-4-(4-Chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Molecular Formula: C42H45ClN8O7S
Molecular Weight: 841.37
Linear Structural Formula: C42H45ClN8O7S
MDL Number: MFCD31692407
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: dBET6 is a highly cell penetrant, potent and selective BET (bromodomain and extra-terminal domain) degrader that induces rapid (<4hrs ) degradation of brd2, brd3 and brd4 and complete down-regulation of c-myc protein and induction of apoptosis. dbet6 exhibits potent anti-cancer activities. <>