Synonyms: AL-108; Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln; L-Asparaginyl-L-alanyl-L-prolyl-L-valyl-L-seryl-L-isoleucyl-L-prolyl-L-Glutamine; NAP; NAP peptide; NAPVSIPQ
Molecular Formula: C36H60N10O12 · xC2HF3O2
Linear Structural Formula: C36H60N10O12 · xC2HF3O2
Purity: >=95% (HPLC)
Storage: -20C
Biochem Physiol Actions: Davunetide (NAPVSIPQ; NAP) is an eight amino acid peptide identified as the active component of activity-dependent neuroprotective protein (ADNP). It has been found to be neuro-protective at femtomolar concentrations in vitro against the neural toxicity of a wide range of compounds. Davunetide has been investigated for Parkinson's disease and schizophrenia and in clinical trials for Alzheimner's Disease, targeting microtubule-tau Interaction.