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An inhibitor of γ-secretase, blocking the production of total Aβ in human primary neuronal cultures with an IC50 value of 115 nM and Aβ42 with an IC50 value of 200 nM; reduces brain levels of Aβ in vivo when given orally; indirectly inhibits Notch, affecting cell signaling and cell differentiation.

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Product Detail
Thomas No.
C832U88
Mfr. No.
13197-5
Description
DAPT-5 mg
CAS Number
208255-80-5
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832U89
Mfr. No.
13197-10
Description
DAPT-10 mg
CAS Number
208255-80-5
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832U90
Mfr. No.
13197-25
Description
DAPT-25 mg
CAS Number
208255-80-5
Packaging Size
25 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832U91
Mfr. No.
13197-50
Description
DAPT-50 mg
CAS Number
208255-80-5
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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