Synonym: (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B5
CAS Number: 137-08-6
Linear Formula: HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca
Molecular Weight: 238.27
Beilstein Registry Number: 3769272
EC Number: 205-278-9
MDL Number: MFCD00002766
PubChem Substance ID: 24852721
Application
Precursor in the biosynthesis of coenzyme A.
Biochem/physiol Actions
D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.
Physical Properties
Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.
Assay: ≥99.0%
Optical Activity: [α]20/D +27±2°, c = 5% in H2O
Impurities: ≤0.002% heavy metals
Loss: ≤3% loss on drying
pH: 6.8-7.2 (25 °C, 50 mg/mL in H2O)
Solubility: H2O: soluble50 mg/mL at 25 °C, clear, almost colorless