Synonym: (β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside
CAS Number: 47-94-4
Empirical Formula (Hill Notation): C9H13N3O5
Molecular Weight: 243.22
Beilstein Registry Number: 89175
EC Number: 205-705-9
MDL Number: MFCD00066487
PubChem Substance ID: 24892435
Biochem/physiol Actions
Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.
Assay: ≥90% (HPLC)
Form: crystalline
Storage Temp.: 2-8°C
Gene Information: human ... POLB(5423); mouse ... Cda(72269)