MDL Number: MFCD00130890
Purity: >=95% based on Mol. Wt. 12,327 basis
Storage: -20C
Application: Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.
Biochem Physiol Actions: The ready interconversion of cytochrome c between ferrous and ferric states makes it an efficient biological electron carrier. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal link in the respiratory chain, it forms the essential electron-bridge between the respirable substrates and oxygen.
Quality Level: PREMIUM
Assay: ≥95% based on Mol. Wt. 12,327 basis
Mol. Wt.: mol wt 12327 Da
Storage Temp.: −20°C
Gene Information: cow ... CYC1(512500)