An antagonist/partial agonist of the androgen receptor (IC50 = 26 nM in humans) that has been shown to have clinical use in androgen-dependent conditions such as prostate cancer, hirsutism, and alopecia; suppresses accessory sexual glands and fertility in adult male rats (10 mg/animal/day); induces apoptosis of hepatocytes in rats at 0.3 µM after 72 hours exposure.