Synonyms: CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450 3A4; P450C3; P450PCN1
Storage: -70C
Application: Poster: A Novel, Robust Recombinant Human P450 Biocatalytic SystemPoster: Evaluation of Dry Powder Preparations of Permeabilized Pichia pastoris Cells Expressing Human Cytochrome P450 2D6 Enzyme (CYP2D6) for Drug Metabolite GenerationPoster: Facile Scale-up Biocatalytic Production of P-450 Metabolites Using a Novel Recombinant Human Catalytic SystemPoster: Multi-Cycle Production of Metabolites with human P450 systemsPoster: Rapid identifcation and production of metabolites using CypExpress(TM) 2D6m 3A4 and 2C9Poster: Rapid identifcation and production of metabolites using stabilized dried powder (SDP) of human cytochrome P450S (hCYPS) 2D6, 3A4, and 2C9 engineered in yeastPoster: Utilizing a Novel Biocatalytic Human P450 System for the Multi - Cycle Production of Metabolites
Biochem Physiol Actions: Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds like xenobiotics, pollutants and drug molecules. Cytochrome P450 3A4 (CYP3A4) is one of the isoforms of cytochrome P450 (P450s). CYP3A4 oxidizes more than 90% of marketed drugs through various metabolic processes.
Legal Information: CypExpress is a trademark of Oxford Biomedical Research