Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi.
- Inhibits peptide synthesis in eukaryotic organisms
- Used in protein synthesis in apoptosis
- Study of disease resistance in plant research
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.
Purity ≥94%
Key Applications: Gene expression, Steroidogenesis Studies, Disease resistance Studies
Product Type: Biochemicals
Biochemical Category: Antibiotics
Melting Point: 103 - 115°C
Format: Powder
Solubility: Very soluble in chloroform, methanol, and acetone; moderately soluble in isopropanol, n-butanol and amyl acetate; very slightly soluble in carbon tetrachloride and the saturated hydrocarbons. Cycloheximide solubility in water is about 2% and the solutions are stable for several weeks at pH 3-5 which is the optimum range for stability. Activity is rapidly destroyed by alkaline solutions
Storage & Handling: +4°C