This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.
Synonyms: alpha-Elaterin; alpha-Elaterine
Molecular Formula: C32H44O8
Molecular Weight: 556.69
Linear Structural Formula: C32H44O8
Purity: >=95.0% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Cucurbitacin E is a potent inhibitor of actin depolymerization. Cucurbitacin E is more active than jasplakinolide, and has a different mechanism of action, binding to a different site. Cucurbitacin E binds specifically to filamentous actin (F-actin) forming a covalent bond at residue Cys257, but not to monomeric actin (G-actin), stabilizing F-actin, without affecting actin polymerization or nucleation.
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