Synonym: (a-Methylguanido)acetic acid, N-Amidinosarcosine
CAS Number: 57-00-1
Linear Formula: H2NC(=NH)N(CH3)CH2CO2H
Molecular Weight : 131.13
Beilstein Registry Number: 907175
EC Number: 200-306-6
MDL Number: MFCD00004282
PubChem Substance ID: 24892273
Packaging
10 mg in autosample vial; 50, 100, 500 g in poly bottle
Application
Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.