Synonyms: 3-[(4-Bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-Isothiazolecarboxamide hydrochloride; PF-01371182 hydrochloride
Molecular Formula: C20H24BrF2N5O3S · HCl
Molecular Weight: 568.86
Linear Structural Formula: C20H24BrF2N5O3S · HCl
MDL Number: MFCD20268381
Purity: >=98% (HPLC)
Storage: room temp
Biochem Physiol Actions: CP-547632 is a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 = 11 and 9 nM, respectively). The compound CP-547632 inhibits VEGF and basic FGF-induced angiogenesis in animal models, and inhibits growth of xenograft tumors in mice.
Legal Information: Sold for research purposes under agreement from Pfizer Inc.