Coenzyme A is an essential cofactor in enzymatic acetyl transfer reactions.
- Facilitates removal of lipid peroxides by increasing mobilization of fatty acids
- Promote repair of plasma membranes by activating phospholipid synthesis
The principal biologically active forms of pantothenic acid are coenzyme A (CoA) and acyl carrier protein (ACP). In CoA, the business center of the molecule is the pantothenic acid metabolite 4'-phosphopantetheine. Coenzyme A is comprised of 4'-phosphopantetheine linked by an anhydride bond to the nucloetide adenosine 5'-monophosphate. 4'-Phosphopantetheine itself is comprised of pantothenic acid linked at one end, via an amide bond, to beta-mercaptoethylamine, derived from L-cysteine, and at the other end to a phosphate group. The sulfhydryl group of 4'-phosphopantetheine, which is the business end of the coenzyme, forms thioesters with acyl groups producing acyl-CoA derivatives, including acetyl-CoA.
Purity: ≥96%
Product Type: Proteins, Enzymes & Peptides
Biochemical Category: Proteins, Enzymes & Peptides
UV/Visible Absorbance: 0.80 - 0.89 (OD250/OD260 (pH 2))
Presentation: White crystalline powder
Solubility: Soluble in water (50 mg/mL - clear, colorless to faint yellow solution)
Storage & Handling: -20°C