Synonyms: [5-Fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl] pyrrolidine-1-carboxylate
Molecular Formula: C19H21FN4O3S
Molecular Weight: 404.46
Linear Structural Formula: C19H21FN4O3S
MDL Number: MFCD28166314
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: CLP290 is a small molecule enhancer of KCC2 activity. It is an orally active and more bioavailable precursor of the selective K+-Cl- cotransporter KCC2 activator CLP257. CLP290 was recently shown to restore Cl- transport and rescue morphine-induced hyperalgesia (MIH) in morphine-treated rats.