Synonyms: ((Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid
Molecular Formula: C16H26N2O5S
Molecular Weight: 358.45
Linear Structural Formula: C16H26N2O5S
Storage: -20C
Biochem Physiol Actions: Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing beta-lactamases. By this action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.