A selective inhibitor of PKC-induced NF-κB pathway activation (IC50 = 0.07 μM); inhibits IL-8 production in HEK293 cells (IC50 ≤ 0.1 μM), attenuates production of IL-2 by Jurkat T cells (IC50 ≤ 5 μM), and prevents proliferation of mouse B-lymphocytes (IC50 = ∼2 μM).