Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry.
Choline chloride is used as a substrate for choline acetyl transferase.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes.
Purity: ≥98.0%
Assay: ≥98.0% (anhydrous basis)
Suitability: Suitable for use as a substrate for choline acetyl transferase.
Key Applications: Substrate for choline acetyl transferase
Application Areas: Cell Biology & Analysis
Product Type: Biochemicals
Density: 1.1 g/cm3 at 20°C (Lit.)
Melting Point: 302-305°C (dec.)(lit.)
Vapor Pressure: 10 hPa at 20°C (Lit.)
Presentation: White Crystalline Powder
Format White: crystalline powder
pH: Neutral to Litmus
Heavy Metals: ≤10 ppm (as Pb)
Residue on ignition: ≤0.1%
Water Content: ≤0.5%
NOTES: 1,4-Dioxane ≤10 ppm
Solubility: Slightly soluble in water (10 % aq. Soln - Clear and Colorless).
Storage & Handling: Store at Room Temperature (15-30°C),dessicate.