Synonyms: CGP 3466B; Dibenz[b,f]oxepin-10-methanamine, N-methyl-N-2-propyn-1-yl-, (2Z)-2-butenedioate (1:1); N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-methyl-N-(2-propynyl)amine monomaleic acid salt; Omigapil maleate salt; TCH346
Molecular Formula: C19H17NO · C4H4O4
Molecular Weight: 391.42
Linear Structural Formula: C19H17NO · C4H4O4
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: CGP3466B, also known as Omigapil maleate and TCH346, is a potent inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It has been shown to have neuroprotective activity and received U.S. FDA Fast Track Designation for the treatment of congenital muscular dystrophy in May 2016.