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A non-lipid inhibitor of cellular ceramidase activity (IC50 = 28 μM in a cell-based assay); induces the accumulation of endogenous ceramide species and decreases intracellular levels of sphingosine and S1P; inhibits cell proliferation of ovarian cancer cells in vitro (IC50 = 0.71 μM) and suppresses tumor growth in a syngeneic tumor model.

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Product Detail
Thomas No.
C833Z84
Mfr. No.
11092-5
Description
Ceranib-2-5 mg
CAS Number
1402830-75-4
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C833Z85
Mfr. No.
11092-10
Description
Ceranib-2-10 mg
CAS Number
1402830-75-4
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C833Z86
Mfr. No.
11092-25
Description
Ceranib-2-25 mg
CAS Number
1402830-75-4
Packaging Size
25 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C833Z87
Mfr. No.
11092-50
Description
Ceranib-2-50 mg
CAS Number
1402830-75-4
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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