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MilliporeSigma

CCT137690 >=98% (HPLC)

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Synonyms: 6-Bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-3H-imidazo[4,5-b]pyridine

Molecular Formula: C26H31BrN8O

Molecular Weight: 551.48

Linear Structural Formula: C26H31BrN8O

MDL Number: MFCD18206879

Purity: >=98% (HPLC)

Storage: -20C

Biochem Physiol Actions: CCT137690 is a very potent, orally bioavailble, pan aurora kinase inhbitor (IC50 = 15, 25, and 19 nM for Aurora A, B and C respectively). CCT137690 inhibits tumor growth in amouse xenograft model and causes multipolar spindle formation, chromosome misalignment, polyploidy and apoptosis in tumor cell lines.

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Product Detail
Thomas No.
CHM03P711
Mfr. No.
SML1237-5MG
Description
SML1237-5MG, CCT137690 >=98% (HPLC)
CAS Number
1095382-05-0
list price/quantitytotal
$0.00
$0.00 (0 Items)
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