Synonyms: (8S)-3,8-Bis[[(1,1-dimethylethoxy)carbonyl]amino]-9-oxo-2,4,10,17-tetraazaoctadec-3-enedioic acid 1-(1,1-dimethylethyl) 18-(phenylmethyl) ester
Molecular Formula: C35H58N6O9
Molecular Weight: 706.87
Linear Structural Formula: C35H58N6O9
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that inhibits the phosphorylation of eIF4E binding protein 1 (4EBP1) and blocks 68% of translation. Cbz-B3A binds to ubiquilins 1, 2, and 4, which prevents mTORC1 activation.
Other Notes: Light and air sensitive.