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A potent inhibitor of PI3Kγ, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively); inhibits phosphorylation of PKB/Akt in mouse macrophages (IC50 = 228 nM).