Recombinant Cas9-D10A Nickase protein from Streptococcus pyogenes (~160 KD) is a ready-to-use reagent for genome engineering experiments. When combined with target-specific paired guide RNAs, S. pyogenes Cas9-D10A nickase will act as a targeted nuclease suitable for transfection of cell cultures and for the accelerated development of genetically-modified animals via one-cell embryo injection.
Synonyms: Cas9 Nickase; Cas9D10A; Nickase Cas9
Purity: >=95% (SDS-PAGE)
Storage: -20C
Application: Functional Genomics/Target Validation/Genome Editing
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