Synonyms: 1,3,7-Trimethylxanthine
Formula: C8H10N4O2
Formula Weight: 194.19
CAS No.: 58-08-2
Biochem/physiol Actions: A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Caution: Keep tightly sealed.
Legal Information: ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
Packaging: 1 kg in poly bottle
Packaging: 5, 100 g in poly bottle
Color: white
Form: powder
Gene Information: human ... ADORA1, ADORA2A
Grade: ReagentPlus®
MP: 234-236.5°C(lit.)
Solubility: H2O: soluble15 mg/mL