Synonyms: 1,1'-[[9-(Hydroxyimino)-9H-fluorene-2,7-diyl]bis(sulfonyl)]bis-piperidine; 2,7-bis(1-Piperidinylsulfonyl)-9H-fluoren-9-one oxime; CIL56
Molecular Formula: C23H27N3O5S2
Molecular Weight: 489.61
Linear Structural Formula: C23H27N3O5S2
MDL Number: MFCD00323348
Purity: >=97% (HPLC)
Storage: -20C
Biochem Physiol Actions: CA3 is a potent and selective inhibitor of YAP1 (Hippo co-activator Yes-associated protein 1) that inhibits YAP1 expression and transcriptional activity in esophageal adenocarcinoma (EAC) cell lines. CA3 potently inhibits growth, induces apoptosis in radiation resistant CSC (cancer stem cell) enriched EAC cells. It inhibits tumor growth of in xenograft model with no apparent toxicity.