Synonyms: 3-(4-((Bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propane-1-sulfonic acid; Copper click-chemistry ligand; Water-soluble CuAAC ligand
Molecular Formula: C20H34N10O3S
Molecular Weight: 494.61
Linear Structural Formula: C20H34N10O3S
Storage: 2-8C
Application: BTTES is a a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTES are advancements from water-insoluble TBTA and are desirable for bioconjugation in diverse chemical biology experiments.
Other Notes: Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne CycloadditionIncreasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative StudyBiocompatible copper(I) catalysts for in vivo imaging of glycans