Synonyms: 2-(4-((Bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid; Copper click-chemistry ligand; Water-soluble CuAAC ligand
Molecular Formula: C19H30N10O2
Molecular Weight: 430.51
Linear Structural Formula: C19H30N10O2
MDL Number: MFCD29918287
Purity: >=95%
Storage: 2-8C
Application: BTTAA is a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTAA are advancements from water-insoluble TBTA and are desirable for bio conjugation in diverse chemical biology experiments.
Other Notes: Biocompatible click chemistry enabled compartment-specific pH measurement inside E. coliFast, cell-compatible click chemistry with copper-chelating azides for biomolecular labelingMetabolic labeling of fucosylated glycoproteins in Bacteroidales speciesIncreasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study