Synonyms: 5-(Benzylthio)-1H-tetrazole solution
Molecular Formula: C8H8N4S
Molecular Weight: 192.24
Linear Structural Formula: C8H8N4S
MDL Number: MFCD00068731
Purity: 51.9-63.4 g/L (BTT content, titration)
Other Notes: Activator solution, containing 5-(Benzylthio)-1H-Tetrazole (BTT or BMT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step. The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.