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BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC50 value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7. BS-181 has been shown to inhibit the phosphorylation of Cdk7 substrates, to promote cell cycle arrest and apoptosis, to inhibit the growth of cancer cell lines in vitro, and to inhibit the growth of MCF-7 human xenografts in nude mice.

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Product Detail
Thomas No.
C815D44
Mfr. No.
17996-1
Description
BS-181-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C815D45
Mfr. No.
17996-5
Description
BS-181-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C815D46
Mfr. No.
17996-10
Description
BS-181-10 mg
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C815D47
Mfr. No.
17996-50
Description
BS-181-50 mg
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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