Source: Recombinant N-terminal GST-tagged protein expressed in E. coli
Mr: 41.2 kDa
BRDT shares homology with the RING3 protein. The two bromodomains of BRDT recognize acetylated histone H4. Loss of BRDT leads to defects in spermatogenesis. In addition to testis specific expression, BRDT was found in approximately 20% of non-small cell lung cancers.