Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide monohydrate; 4-Tert-butyl-N- [6-(2-hydroxyethoxy)-5-(2-methoxy-phenoxy)-[2,2´]-bipyrimidin-4-yl]-benzenesulfonamide monohydrate; Ro-47-0203
Molecular Formula: C27H29N5O6S · H2O
Molecular Weight: 569.63
Linear Structural Formula: C27H29N5O6S · H2O
MDL Number: MFCD09751188
Purity: >=98% (HPLC)
Storage: 2-8C
Application: Bosentan hydrate has been used in cell viability assay. It has also been used as a positive control for calcium transient analysis.
Biochem Physiol Actions: Bosentan is found to decrease deposition of collagen in the lungs, which has been observed in bleomycin-induced pulmonary fibrosis rat model.