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MilliporeSigma

BioTracker Cystine-FITC Live Cell Dye Live cell imaging dye that measures cystine uptake at the single cell level used to detect glutathione (GSH) synthesis, reactive oxygen species (ROS) detoxification, T-cell activation and B-cell development.

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Uptake of cystine allows accumulation of cysteine that is necessary for glutathione synthesis and reactive oxygen species (ROS) detoxification. After the uptake of cystine into the cytoplasm, the reducing intracellular environment leads to a separation of one cystine molecule into two cysteine molecules. A key function of cysteine is to maintain the cellular pools of glutathione (GSH). Cystine uptake is also required for T-cell activation and B-cell development.The BioTracker Cystine-FITC dye is a live cell green fluorescent imaging probe that measures cystine uptake at the single cell level. The probe has been used to measure T-cell activation using traditional and imaging flow cytometry methods. Spectral PropertiesAbsorbance: 450nmEmission: 525nm

Synonyms: Live cell imaging probe

Purity: >=98% (H-NMR); >=98% (HPLC); >=98% (LC/MS); >=98% (elemental analysis)

Application: Research Sub CategoryLive Cell Dye

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Product Detail
Thomas No.
CHM02G465
Mfr. No.
SCT047
Description
SCT047, BioTracker Cystine-FITC Live Cell Dye Live cell imaging dye that measures cystine uptake at the single cell level used to detect glutathione (GSH) synthesis, reactive oxygen species (ROS) detoxification, T-cell activation and B-cell development.
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