Synonyms: N-(2-((2-Aminoethyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2,2,2-trifluoroacetate; Biotin-SS-NH2 TFA; Biotin-cystamine TFA; Cleavable biotin linker
Molecular Formula: C16H27F3N4O4S3
Molecular Weight: 492.6
Linear Structural Formula: C16H27F3N4O4S3
MDL Number: MFCD26793862
Storage: -20C
Application: Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid (Biotin-SS-NH2 TFA) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.
Other Notes: Fluorometric assay for tissue transglutaminase-mediated transamidation activityConvenient Synthesis of Photoaffinity Probes and Evaluation of Their Labeling AbilitiesA simple photo-affinity labeling protocol