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Cayman Chemical

BI-847325

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BI-847325

A selective dual MEK/Aurora kinase inhibitor (IC50s = 3, 25, 15, 25, and 4 nM for X. laevis Aurora B, human Aurora A and Aurora C, and human MEK1 and MEK2, respectively); inhibits the growth and survival of both treatment-naïve and drug-resistant melanoma both in vitro and in vivo, decreasing the expression of MEK and Mcl-1 while increasing the expression of pro-apoptotic protein Bim.

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Product Detail
Thomas No.
C815J87
Mfr. No.
18301-1
Description
BI-847325-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C815J88
Mfr. No.
18301-5
Description
BI-847325-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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