Synonyms: (2E)-N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide; (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide; (E)-N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide; PX 105684; PX-105684; PX105684; PXD 101; PXD-101; PXD101
Molecular Formula: C15H14N2O4S
Molecular Weight: 318.35
Linear Structural Formula: C15H14N2O4S
MDL Number: MFCD08064035
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: Belinostat (PX105684; PXD101) is a potent, hydroxamate class pan-selective histone deacetylases (HDACs) inhibitor (IC50: class I HDAC1/2/3/8 = 41/125/30/216 nM, class IIA HDAC4/7/9 = 115/67/128 nM, class IIB HDAC6 = 82 nM) with anti-cancer efficacy in vitro and in vivo.