Synonyms: 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid; 2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]-benzoic acid
Molecular Formula: C20H14ClNO5S
Molecular Weight: 415.85
Linear Structural Formula: C20H14ClNO5S
MDL Number: MFCD05157149
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: BAY-8002 is an orally available, potent and selective inhibitor of lactate transporter MCT1 (monocarboxylate transporter 1; SLC16A1) that potently inhibits bidirectional lactate transport. BAY-8002 exhibits antiproliferative activity in numerous cancer cell lines. BAY-8002 induces accumulation of lactate and significantly inhibits tumor growth in mice model. It does not cause tumor regression.