Synonyms: (S)-N-Ethyl-4-(3-methylmorpholino)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Molecular Formula: C15H20N4O2
Molecular Weight: 288.34
Linear Structural Formula: C15H20N4O2
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage. BAY-707 was shown to be a substrate-competitive, selective MTH1 inhibitor with an IC50 value of 2.3 nM.