Synonyms: 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
Molecular Formula: C25H23N3O4
Molecular Weight: 429.47
Linear Structural Formula: C25H23N3O4
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: BAY-299 is a potent and selective inhibitor of BRD1 and the second bromodomain of TAF1 (Transcription initiation factor TFIID subunits 1). BAY-299 is selective over other bromodomains including the other members of the BRPF family, and BRD9, ATAD2 and BRD4. BAY-364 is structurally similar to BAY-299 and serves as inactive control. For full characterization details, please visit the BAY-299 probe summary on the Structural Genomics Consortium (SGC) website.BAY-364 (BAY-299N) is the negative control for the active, structurally similar probe, BAY-299. BAY-364 is available from Sigma. To learn more about and purchase BAY-364, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc