Synonym: ß-NADPH, 2'-NADPH, Coenzyme II reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt, NADPH Na4, TPNH2 Na4, Triphosphopyridine nucleotide reduced tetrasodium salt
Empirical Formula (Hill Notation) : C21H26N7Na4O17P3
Molecular Weight: 833.35
EC Number: 220-163-3
MDL number: MFCD00036263
PubChem Substance ID: 24897910
Other Notes
Packaged based on NADPH content as determined by UV-Vis.
Preparation Note
Chemically reduced
Application
ß-Nicotinamide adenine dinucleotide 2'-phosphate (NADP+) and ß-Nicotinamide adenine dinucleotide 2'-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
Biochem/physiol Actions
ß-Nicotinamide adenine dinucleotide 2'-phosphate (NADP+) and ß-Nicotinamide adenine dinucleotide 2'-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).