Synonym: BGP, Glycerol 2-phosphate disodium salt hydrate
CAS Number: 154804-51-0
Linear Formula: (HOCH2)2CHOP(O)(ONa)2 · xH2O
Molecular Weight: 216.04 (anhydrous basis)
EC Number: 212-454-3
MDL Number: MFCD00149082
Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.
Product Line: BioUltra
Assay: ≥99.0% (titration)
Impurities: ≤0.1% Insoluble matter, ≤0.5 mol % L-α-isomer
MP: 102-104 °C(lit.)
Anion Traces: chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.05%
Cation Traces: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.005%; Mg: ≤0.0005%; Pb: ≤0.001%; Zn: ≤0.0005%
Suitability: suitable for cell culture, suitable for plant cell culture