Synonyms: 4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one; 4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone; AZD 2461; AZD-2461
Molecular Formula: C22H22FN3O3
Molecular Weight: 395.43
Linear Structural Formula: C22H22FN3O3
MDL Number: MFCD24386811
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: AZD2461, an olaparib analog, is an orally available, potent and selective PARP1 and PARP2 inhibitor that is a poor substrate for drug transporters. AZD2461 exhibits a high efficacy in olaparib-resistant tumors that overexpress P-glycoprotein.