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Cayman Chemical

Avagacestat

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Avagacestat

A potent, orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP to Aβ40 than signaling through Notch (IC50s = 0.30 and 58 nM, respectively); shows good pharmacokinetics in rats, dogs, and humans and passes the blood-brain barrier, reducing plasma, brain, and cerebrospinal fluid Aβ40 levels.

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Product Detail
Thomas No.
C817X53
Mfr. No.
16711-1
Description
Avagacestat-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X54
Mfr. No.
16711-5
Description
Avagacestat-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X55
Mfr. No.
16711-10
Description
Avagacestat-10 mg
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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