Synonyms: (SP-4-2)-dichloro(4,4'-dimethoxy-2,2'-bipyridine-kN1,kN1')-Gold(1+), hexafluorophosphate(1-); [Au(4,4'-dimethoxy-2,2'-bipyridine)Cl2][PF6]
Molecular Formula: C12H12AuCl2N2O2 · PF6
Molecular Weight: 629.07
Linear Structural Formula: C12H12AuCl2N2O2 · PF6
Purity: >=97% (NMR)
Storage: 2-8C
Biochem Physiol Actions: AubipyOMe is a potent inhibitor of tartrate resistant acid phosphatase (TRAP/ACP5), a metalloenzyme expressed in activated osteoclasts and in macrophages. AubipyOMe exhibited IC50 values of 1.3 muM for TRAP5a and 1.8 muM for TRAP5b and inhibited TRAP activity in murine macrophage and human lung tissue extracts.