An anthranilic acid derivative that activates the oxidized (heme-free) form of sGC (EC50 = 0.5-10 µM in purified bovine lung or crude human corpus cavernosum) by binding to the heme pocket and mimicking its function; increases cGMP levels in cultured rat aorta smooth muscle cells and induces vasorelaxation of isolated rat aorta, porcine coronary arteries, and human corpus cavernosum isolates (EC50 = 1-10 µM).