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MilliporeSigma

AS8351 >=98% (HPLC)

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AS8351 >=98% (HPLC)

Synonyms: 2-Hydroxy-1-naphthylaldehyde isonicotinoylhydrazone; 311 Iron Chelator; AS-8351; NSC-51355

Molecular Formula: C17H13N3O2

Molecular Weight: 291.3

Linear Structural Formula: C17H13N3O2

MDL Number: MFCD00033110

Purity: >=98% (HPLC)

Storage: -20C

Biochem Physiol Actions: AS8351 is an iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B), a histone H3K4 demethylase involved in regulation of cell proliferation and stem cell self-renewal and differentiation. AS8351 is thought to inhibit KDM5B by competing with a-ketoglutarate for chelating iron that KDM5B requires as a co-factor.

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Product Detail
Thomas No.
CHM02U517
Mfr. No.
SML1692-5MG
Description
SML1692-5MG, AS8351 >=98% (HPLC)
CAS Number
796-42-9
list price/quantitytotal
$0.00
$0.00 (0 Items)
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