A potent, stable, and selective agonist analog of AEA with a Ki value of 1.4 nM at the isolated rat CB1 receptor; 1,400 times more potent at the CB1 compared with the CB2 receptor; induces hypothermia in mice with the same efficacy as AEA, in spite of its much higher affinity for the CB1 receptor and thus is a possible substrate for FAAH.