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MilliporeSigma

API-1

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API-1

Synonyms: 4-Amino-5,8-dihydro-5-oxo-8-b-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; NSC 177223; NSC177223

Molecular Formula: C13H15N5O6

Molecular Weight: 337.29

Linear Structural Formula: C13H15N5O6

MDL Number: MFCD18086904

Purity: >=95% (HPLC)

Storage: -20C

Biochem Physiol Actions: API-1 is a potent and specific Akt/PKB inhibitor. API-1 binds to pleckstrin homology (PH) domain of Akt and blocks Akt membrane translocation. The compound inhibits all three members of the family Akt1/PKBa, Akt2/PKBb and Akt3/PKBg. API-1 does not inhibit the activation of PKC, SGK, PKA, STAT3, Erk-1/2 or JNK.

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Product Detail
Thomas No.
CHM02U460
Mfr. No.
SML1342-5MG
Description
SML1342-5MG, API-1
CAS Number
36707-00-3
UN Number
UN2811
list price/quantitytotal
$0.00
$0.00 (0 Items)
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